Nerivio: From worth to efficacy, all you’ll want to find out about drug-free remedy for migraine

“Nerivio® is the primary and solely USFDA authorised system to use Distant Electrical Neuromodulation (REN) to stop and treat migraine,” the drug maker stated in a press release.

“The rollout of Nerivio marks our entry into digital therapeutics. It’s an area that’s seeing growing adoption by physicians in addition to sufferers because of its potential to scale back capsule burden and reduce dependency on non-particular treatment in persistent or onerous-to-treat illnesses,” Dr Reddy’s CEO Branded Markets (India and Emerging Markets) MV Ramana stated.

This is all it’s essential to know about Nerivio, the drug-free remedy for migraine:

What is Nerivio?

Dr Reddy’s Laboratories stated Nerivio is a prescription-based mostly non-invasive gadget meant for acute and prophylactic (preventive) remedy of migraine.

Who can use Nerivio?

The drug-maker stated the gadget is for individuals aged 12 years and above.

“Nerivio® is appropriate for a wide range of patients, including those who choose drug-free options, individuals with contraindications to drugs or poor treatment tolerance, delicate populations similar to adolescents, ladies of weak age teams and sufferers liable to treatment overuse headaches,” it added.

How environment friendly it’s?

Dr Reddy’s stated Nerivio® proved “efficacy in not solely effectively treating aid of pain but in addition related symptoms in migraine akin to nausea, vomiting and so forth. It has been shown to scale back the need for medicine used for acute remedy in almost nine out of 10 patients”.

How much does it value?

In line with a Occasions of India report, Nerivio has been priced at 14,000-sixteen,000.

Who shouldn’t use it?

“The gadget should not be utilized by individuals with uncontrolled epilepsy and people with an lively implantable medical system, similar to a pacemaker, hearing help implant, or any implanted electronic gadget,” in accordance with Theranica.

Dr Reddy’s stated it entered into an exclusive settlement with Theranica in January 2023 for the advertising and distribution of Nerivio® in India. Theranica is a prescribed digital therapeutics firm creating advanced neuromodulation units for migraine and other ache circumstances.

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How is Nerivio used?

The gadget might be worn on the upper arm. It must be used within 60 minutes of onset of headache for acute remedy of migraine or every alternate day for prevention of migraine, the drug maker was quoted by PTI as saying.

The system should only be applied on the upper arm over dry, healthy skin with regular physical sensation and without any metallic implants or in proximity to cancerous lesions.

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“Every system has in-constructed 18 x 45-minute (18 periods of 45 minutes every) remedy periods,” Dr Reddy’s stated. After 18 periods, the system needs to be discarded for a recent one. An app can be utilized to regulate the intensity ranges of the system.

This consumer-friendly app – Nerivio app – comes with in-built features akin to an interactive migraine diary to log signs, monitor responses and share insightful analytics.

“The app also consists of an interactive GIER (guided, imagery, schooling and rest) protocol which, if used with Nerivio®, considerably will increase the response rates,” the drug maker stated.

The app could be downloaded from Google Play Store and the Apple app retailer.

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How does it work?

Dr Reddy’s explained that the system uses the Remote Electrical Neuromodulation (REN) mechanism to particularly activate conditioned pain modulation by stimulating nerve endings. “This initiates a natural pain-relieving process within the brainstem, causing a worldwide effect of ache inhibition that impacts the original source of migraine pain in the head,” it added.

For details, watch the video under:

What does the remedy really feel like?

In line with the Nerivio website, the system transmits electrical pulses. The consumer might want to set the remedy intensity degree by growing it to the very best degree that feels robust but snug and painless.

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“Chances are you’ll feel a robust sensation at first, but it is going to sometimes fade to a cushty degree after a couple of seconds. If the sensation is uncomfortable or painful, you must decrease the depth,” it explains.

One may additionally experience a short lived sensation of warmth, local tingling, numbness in the arm, pain in the arm, or redness of the skin.

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Updated: 18 Nov 2023, 08:20 AM IST

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